Chemistry Controls, Calibrators and Reagents

Products for use in performing, calibrating, monitoring, and ensuring the accuracy of a variety of clinical chemistry procedures.

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ABclonal Technology Cardiac Troponin I (TNNI3) Rabbit pAb

Troponin I (TnI) is one of three subunits of the troponin complex in striated muscle, acting as the inhibitory component that blocks actin-myosin interactions to mediate muscle relaxation. This gene encodes the cardiac-specific isoform, expressed exclusively in heart tissue. Mutations are linked to familial hypertrophic cardiomyopathy type 7 (CMH7) and restrictive cardiomyopathy (RCM). TnI is a key biomarker for diagnosing heart failure and ischemic heart disease. Elevated troponin levels are also used to detect acute myocardial injury in moderate to severe COVID-19 cases and are associated with increased mortality in cardiovascular patients hospitalized with COVID-19.